Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZDHHC16. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZDHHC16 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZDHHC16, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:97,179,559–97,180,186 | 266.2 kb | Distal (>10kb) Multiome | 190 | |
| chr10:97,185,462–97,186,037 | 260.2 kb | Distal (>10kb) Multiome | 248 | |
| chr10:97,195,967–97,196,850 | 249.6 kb | Distal (>10kb) Multiome | 469 | |
| chr10:97,291,972–97,293,103 | 153.5 kb | Distal (>10kb) Multiome | 945 | |
| chr10:97,318,840–97,320,386 | 127.0 kb | Distal (>10kb) Multiome | 836 | |
| chr10:97,333,472–97,335,742 | 111.2 kb | Distal (>10kb) Multiome | 917 | |
| chr10:97,336,929–97,337,706 | 108.9 kb | Distal (>10kb) Multiome | 362 | |
| chr10:97,400,817–97,401,691 | 44.9 kb | Distal (>10kb) Multiome | 644 | |
| chr10:97,407,246–97,407,739 | 38.7 kb | Distal (>10kb) Multiome | 539 | |
| chr10:97,418,830–97,419,461 | 27.0 kb | Distal (>10kb) Multiome | 323 | |
| chr10:97,425,050–97,426,796 | 20.0 kb | Distal (>10kb) Multiome | 715 | |
| chr10:97,445,521–97,446,585 | 10 bp | At TSS Multiome | 802 | |
| chr10:97,497,718–97,499,773 | 52.5 kb | Distal (>10kb) Multiome | 967 | |
| chr10:97,553,598–97,554,047 | 107.6 kb | Distal (>10kb) Multiome | 340 | |
| chr10:97,632,775–97,633,915 | 187.3 kb | Distal (>10kb) Multiome | 725 | |
| chr10:97,640,236–97,641,335 | 194.4 kb | Distal (>10kb) Multiome | 712 | |
| chr10:97,686,724–97,687,987 | 241.2 kb | Distal (>10kb) Multiome | 993 | |
| chr10:97,713,223–97,715,263 | 267.6 kb | Distal (>10kb) Multiome | 639 | |
| chr10:97,736,595–97,737,824 | 290.9 kb | Distal (>10kb) Multiome | 1009 |
Genomic view of the ZDHHC16 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.