Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZDHHC14. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZDHHC14 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZDHHC14, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:157,235,403–157,237,021 | 145.3 kb | Distal (>10kb) Multiome | 380 | |
| chr6:157,274,253–157,275,484 | 106.2 kb | Distal (>10kb) Multiome | 761 | |
| chr6:157,379,723–157,382,345 | 1.1 kb | Proximal (<10kb) Multiome | 926 | |
| chr6:157,533,250–157,533,761 | 152.4 kb | Distal (>10kb) Multiome | 237 | |
| chr6:157,552,274–157,553,166 | 171.4 kb | Distal (>10kb) Multiome HiCAR | 219 | |
| chr6:157,597,582–157,598,179 | 4.8 kb | Proximal (<10kb) | 300 | |
| chr6:157,708,186–157,708,676 | 327.3 kb | Distal (>10kb) Multiome | 16 | |
| chr6:157,822,586–157,824,197 | 442.0 kb | Distal (>10kb) Multiome | 842 |
Genomic view of the ZDHHC14 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.