Enables RNA binding activity. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZCCHC24. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZCCHC24 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZCCHC24, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:79,157,212–79,158,222 | 287.9 kb | Distal (>10kb) Multiome | 633 | |
| chr10:79,195,004–79,195,734 | 250.1 kb | Distal (>10kb) Multiome | 517 | |
| chr10:79,239,374–79,240,591 | 205.3 kb | Distal (>10kb) Multiome | 318 | |
| chr10:79,242,182–79,244,115 | 202.1 kb | Distal (>10kb) Multiome | 517 | |
| chr10:79,344,555–79,345,573 | 100.8 kb | Distal (>10kb) Multiome | 144 | |
| chr10:79,346,612–79,348,513 | 98.3 kb | Distal (>10kb) Multiome | 939 | |
| chr10:79,444,238–79,447,010 | 179 bp | At TSS Multiome | 851 | |
| chr10:79,454,165–79,454,609 | 8.5 kb | Proximal (<10kb) | 64 | |
| chr10:79,487,460–79,487,935 | 42.1 kb | Distal (>10kb) Multiome | 240 | |
| chr10:80,204,736–80,206,157 | 760.0 kb | Distal (>10kb) Multiome HiCAR | 830 | |
| chr10:80,207,076–80,207,999 | 761.9 kb | Distal (>10kb) Multiome HiCAR | 466 |
Genomic view of the ZCCHC24 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.