Predicted to be involved in cell differentiation. Located in Golgi apparatus and transport vesicle. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for YIPF3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = YIPF3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of YIPF3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:43,228,982–43,229,794 | 287.5 kb | Distal (>10kb) Multiome HiCAR | 918 | |
| chr6:43,246,576–43,247,616 | 269.7 kb | Distal (>10kb) Multiome | 750 | |
| chr6:43,267,244–43,268,167 | 249.2 kb | Distal (>10kb) Multiome | 772 | |
| chr6:43,285,054–43,285,508 | 231.6 kb | Distal (>10kb) Multiome | 68 | |
| chr6:43,308,219–43,309,149 | 208.1 kb | Distal (>10kb) Multiome | 462 | |
| chr6:43,368,714–43,370,143 | 147.3 kb | Distal (>10kb) Multiome | 909 | |
| chr6:43,426,936–43,428,340 | 89.3 kb | Distal (>10kb) Multiome | 919 | |
| chr6:43,454,362–43,454,991 | 62.2 kb | Distal (>10kb) Multiome | 686 | |
| chr6:43,477,347–43,478,043 | 39.4 kb | Distal (>10kb) Multiome | 747 | |
| chr6:43,506,605–43,507,204 | 10.0 kb | Distal (>10kb) Multiome | 474 | |
| chr6:43,509,337–43,511,016 | 6.6 kb | Proximal (<10kb) Multiome | 734 | |
| chr6:43,516,463–43,517,515 | 79 bp | At TSS Multiome | 904 | |
| chr6:43,575,269–43,576,483 | 59.1 kb | Distal (>10kb) Multiome | 1044 | |
| chr6:43,628,488–43,630,447 | 113.3 kb | Distal (>10kb) Multiome | 1157 | |
| chr6:43,635,496–43,636,104 | 118.9 kb | Distal (>10kb) Multiome | 941 | |
| chr6:43,644,712–43,645,902 | 128.4 kb | Distal (>10kb) Multiome | 255 | |
| chr6:43,667,273–43,667,900 | 150.4 kb | Distal (>10kb) Multiome | 625 | |
| chr6:43,667,997–43,668,873 | 151.5 kb | Distal (>10kb) Multiome | 664 | |
| chr6:43,695,239–43,695,940 | 178.8 kb | Distal (>10kb) Multiome | 207 | |
| chr6:43,702,335–43,703,403 | 186.1 kb | Distal (>10kb) Multiome | 713 | |
| chr6:43,706,840–43,708,370 | 191.0 kb | Distal (>10kb) Multiome | 307 | |
| chr6:43,739,421–43,740,065 | 222.8 kb | Distal (>10kb) Multiome | 175 | |
| chr6:43,769,188–43,772,162 | 253.1 kb | Distal (>10kb) Multiome | 1112 | |
| chr6:43,774,651–43,775,250 | 258.1 kb | Distal (>10kb) Multiome | 440 |
Genomic view of the YIPF3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.