Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for VSTM2B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = VSTM2B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of VSTM2B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:29,525,368–29,525,779 | 213 bp | At TSS | 133 | |
| chr19:29,525,914–29,526,665 | at TSS | At TSS | 132 | |
| chr19:29,526,770–29,527,553 | 777 bp | At TSS | 188 | |
| chr19:29,528,180–29,529,621 | 2.6 kb | Proximal (<10kb) Multiome | 401 | |
| chr19:29,529,766–29,530,718 | 4.4 kb | Proximal (<10kb) Multiome | 175 | |
| chr19:29,605,720–29,606,615 | 80.2 kb | Distal (>10kb) Multiome | 901 | |
| chr19:29,610,433–29,610,904 | 84.7 kb | Distal (>10kb) Multiome | 320 | |
| chr19:29,665,021–29,667,200 | 140.7 kb | Distal (>10kb) Multiome | 621 | |
| chr19:29,714,800–29,715,683 | 189.2 kb | Distal (>10kb) Multiome | 726 | |
| chr19:29,724,045–29,724,626 | 198.4 kb | Distal (>10kb) Multiome | 189 | |
| chr19:29,759,946–29,760,434 | 234.3 kb | Distal (>10kb) Multiome | 502 | |
| chr19:29,811,175–29,812,847 | 285.8 kb | Distal (>10kb) Multiome | 705 |
Genomic view of the VSTM2B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.