Enables RNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TRNAU1AP. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TRNAU1AP upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TRNAU1AP, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:28,258,840–28,260,822 | 292.7 kb | Distal (>10kb) Multiome | 910 | |
| chr1:28,369,387–28,370,499 | 183.3 kb | Distal (>10kb) Multiome | 961 | |
| chr1:28,505,412–28,506,885 | 47.1 kb | Distal (>10kb) Multiome | 969 | |
| chr1:28,513,136–28,516,505 | 37.6 kb | Distal (>10kb) Multiome | 461 | |
| chr1:28,517,302–28,519,364 | 34.7 kb | Distal (>10kb) Multiome | 927 | |
| chr1:28,552,370–28,553,806 | 104 bp | At TSS Multiome | 955 | |
| chr1:28,580,985–28,582,501 | 28.8 kb | Distal (>10kb) Multiome | 1080 | |
| chr1:28,592,018–28,592,768 | 39.3 kb | Distal (>10kb) Multiome | 394 | |
| chr1:28,642,403–28,643,726 | 90.1 kb | Distal (>10kb) Multiome | 980 | |
| chr1:28,648,003–28,650,002 | 95.8 kb | Distal (>10kb) Multiome | 1377 | |
| chr1:28,667,742–28,669,783 | 115.3 kb | Distal (>10kb) Multiome | 804 | |
| chr1:28,736,098–28,738,080 | 183.6 kb | Distal (>10kb) Multiome | 1106 | |
| chr1:28,811,880–28,812,661 | 259.2 kb | Distal (>10kb) Multiome | 219 |
Genomic view of the TRNAU1AP locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.