Predicted to act upstream of or within response to bacterium. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TMEM255A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TMEM255A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TMEM255A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:120,306,485–120,307,000 | 4.4 kb | Proximal (<10kb) | 48 | |
| chrX:120,308,640–120,308,926 | 2.5 kb | Proximal (<10kb) | 93 | |
| chrX:120,309,330–120,309,857 | 1.6 kb | Proximal (<10kb) | 479 | |
| chrX:120,310,810–120,311,564 | at TSS | At TSS | 179 | |
| chrX:120,319,430–120,319,604 | 8.0 kb | Proximal (<10kb) | 96 |
Genomic view of the TMEM255A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.