Enables UDP-N-acetylglucosamine transmembrane transporter activity. Involved in UDP-N-acetylglucosamine transmembrane transport. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TMEM241. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TMEM241 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TMEM241, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr18:23,133,973–23,134,655 | 303.6 kb | Distal (>10kb) Multiome HiCAR | 505 | |
| chr18:23,134,786–23,136,684 | 302.3 kb | Distal (>10kb) Multiome HiCAR | 757 | |
| chr18:23,259,654–23,260,831 | 177.7 kb | Distal (>10kb) Multiome | 655 | |
| chr18:23,437,346–23,438,074 | 54 bp | At TSS Multiome | 628 | |
| chr18:23,452,793–23,453,775 | 15.3 kb | Distal (>10kb) Multiome | 796 | |
| chr18:23,502,975–23,503,998 | 65.5 kb | Distal (>10kb) Multiome | 907 | |
| chr18:23,586,020–23,587,174 | 148.8 kb | Distal (>10kb) Multiome | 908 | |
| chr18:23,609,370–23,609,991 | 171.8 kb | Distal (>10kb) Multiome | 79 | |
| chr18:23,618,918–23,619,643 | 181.4 kb | Distal (>10kb) Multiome | 295 | |
| chr18:23,662,307–23,663,058 | 224.8 kb | Distal (>10kb) Multiome | 349 | |
| chr18:23,689,205–23,690,311 | 251.6 kb | Distal (>10kb) Multiome | 469 | |
| chr18:23,721,611–23,722,408 | 284.1 kb | Distal (>10kb) Multiome | 82 |
Genomic view of the TMEM241 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.