Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TMEM160. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TMEM160 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TMEM160, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:46,787,215–46,789,013 | 260.0 kb | Distal (>10kb) Multiome | 944 | |
| chr19:46,850,211–46,851,336 | 197.8 kb | Distal (>10kb) Multiome | 946 | |
| chr19:46,855,920–46,856,711 | 192.4 kb | Distal (>10kb) Multiome | 610 | |
| chr19:46,859,815–46,861,611 | 188.3 kb | Distal (>10kb) Multiome | 1061 | |
| chr19:47,019,502–47,020,076 | 28.9 kb | Distal (>10kb) Multiome | 188 | |
| chr19:47,035,599–47,036,293 | 12.6 kb | Distal (>10kb) Multiome | 627 | |
| chr19:47,047,837–47,048,980 | 711 bp | At TSS Multiome | 760 | |
| chr19:47,058,561–47,059,308 | 10.3 kb | Distal (>10kb) Multiome | 357 | |
| chr19:47,111,821–47,113,936 | 63.6 kb | Distal (>10kb) Multiome | 1117 | |
| chr19:47,130,439–47,131,651 | 82.2 kb | Distal (>10kb) Multiome | 908 | |
| chr19:47,157,325–47,158,494 | 109.0 kb | Distal (>10kb) Multiome | 271 | |
| chr19:47,196,586–47,197,452 | 148.2 kb | Distal (>10kb) Multiome | 94 | |
| chr19:47,225,386–47,231,990 | 179.2 kb | Distal (>10kb) Multiome | 1389 | |
| chr19:47,240,827–47,241,572 | 192.6 kb | Distal (>10kb) Multiome | 616 | |
| chr19:47,242,713–47,243,645 | 194.5 kb | Distal (>10kb) Multiome | 568 | |
| chr19:47,243,835–47,244,896 | 195.7 kb | Distal (>10kb) Multiome | 1001 | |
| chr19:47,256,041–47,258,057 | 208.5 kb | Distal (>10kb) Multiome | 907 | |
| chr19:47,272,778–47,275,890 | 224.8 kb | Distal (>10kb) Multiome | 931 |
Genomic view of the TMEM160 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.