Enables RNA binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to act upstream of or within cell motility; mechanosensory behavior; and spermatid development. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for STRBP. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = STRBP upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of STRBP, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:123,268,083–123,269,422 | 155 bp | At TSS Multiome | 666 | |
| chr9:123,353,960–123,354,559 | 85.7 kb | Distal (>10kb) Multiome | 362 | |
| chr9:123,359,538–123,361,097 | 91.8 kb | Distal (>10kb) Multiome | 570 | |
| chr9:123,385,057–123,385,832 | 116.9 kb | Distal (>10kb) Multiome | 309 | |
| chr9:123,485,015–123,485,596 | 216.8 kb | Distal (>10kb) Multiome | 39 |
Genomic view of the STRBP locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.