Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for STK32A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = STK32A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of STK32A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:147,040,856–147,042,434 | 192.9 kb | Distal (>10kb) Multiome | 102 | |
| chr5:147,234,227–147,235,490 | 7 bp | At TSS Multiome | 281 | |
| chr5:147,240,262–147,240,586 | 5.2 kb | Proximal (<10kb) | 10 | |
| chr5:147,240,726–147,240,860 | 5.7 kb | Proximal (<10kb) | 4 | |
| chr5:147,384,143–147,385,012 | 149.6 kb | Distal (>10kb) Multiome HiCAR | 122 | |
| chr5:147,393,976–147,394,632 | 159.4 kb | Distal (>10kb) Multiome HiCAR | 84 | |
| chr5:147,452,160–147,452,760 | 217.4 kb | Distal (>10kb) Multiome | 144 | |
| chr5:147,453,007–147,454,909 | 219.0 kb | Distal (>10kb) Multiome | 558 | |
| chr5:147,508,911–147,510,481 | 275.1 kb | Distal (>10kb) Multiome | 440 |
Genomic view of the STK32A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.