Predicted to be involved in carbohydrate metabolic process; cell differentiation; and spermatogenesis. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SPATA20. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SPATA20 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SPATA20, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr17:50,273,066–50,273,646 | 273.9 kb | Distal (>10kb) Multiome | 411 | |
| chr17:50,274,084–50,274,945 | 272.6 kb | Distal (>10kb) Multiome | 242 | |
| chr17:50,310,314–50,311,981 | 235.5 kb | Distal (>10kb) Multiome | 314 | |
| chr17:50,312,127–50,312,775 | 234.5 kb | Distal (>10kb) Multiome | 37 | |
| chr17:50,345,523–50,346,998 | 201.0 kb | Distal (>10kb) Multiome | 809 | |
| chr17:50,363,392–50,364,195 | 183.3 kb | Distal (>10kb) Multiome | 164 | |
| chr17:50,372,860–50,373,487 | 174.0 kb | Distal (>10kb) Multiome | 999 | |
| chr17:50,397,227–50,397,885 | 149.6 kb | Distal (>10kb) Multiome | 1045 | |
| chr17:50,425,595–50,426,626 | 120.9 kb | Distal (>10kb) Multiome | 619 | |
| chr17:50,478,411–50,479,262 | 68.3 kb | Distal (>10kb) Multiome | 956 | |
| chr17:50,508,047–50,508,856 | 38.7 kb | Distal (>10kb) Multiome | 332 | |
| chr17:50,541,672–50,542,697 | 5.0 kb | Proximal (<10kb) Multiome | 772 | |
| chr17:50,546,778–50,547,615 | 11 bp | At TSS Multiome | 786 | |
| chr17:50,550,779–50,551,160 | 3.6 kb | Proximal (<10kb) | 410 | |
| chr17:50,558,590–50,561,781 | 13.4 kb | Distal (>10kb) Multiome | 587 | |
| chr17:50,586,525–50,587,142 | 39.6 kb | Distal (>10kb) Multiome | 43 | |
| chr17:50,634,652–50,635,325 | 87.9 kb | Distal (>10kb) Multiome HiCAR | 471 | |
| chr17:50,707,179–50,708,006 | 160.5 kb | Distal (>10kb) Multiome HiCAR | 1055 | |
| chr17:50,719,167–50,720,018 | 172.4 kb | Distal (>10kb) Multiome | 1050 | |
| chr17:50,950,043–50,950,638 | 403.4 kb | Distal (>10kb) Multiome HiCAR | 713 |
Genomic view of the SPATA20 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.