Predicted to be involved in cartilage development. Predicted to be located in several cellular components, including collagen-containing extracellular matrix; cytoplasm; and extracellular region. Predicted to be active in cell periphery. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for SNORC. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNORC upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNORC, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:232,605,843–232,606,606 | 270.3 kb | Distal (>10kb) Multiome | 604 | |
| chr2:232,633,106–232,634,804 | 243.0 kb | Distal (>10kb) Multiome | 747 | |
| chr2:232,696,754–232,698,213 | 179.2 kb | Distal (>10kb) Multiome | 927 | |
| chr2:232,875,994–232,877,248 | 36 bp | At TSS Multiome | 488 | |
| chr2:232,927,461–232,929,198 | 51.8 kb | Distal (>10kb) Multiome | 215 | |
| chr2:233,051,257–233,052,137 | 175.3 kb | Distal (>10kb) Multiome | 218 | |
| chr2:233,129,373–233,130,063 | 253.1 kb | Distal (>10kb) Multiome | 111 | |
| chr2:233,139,260–233,139,740 | 262.9 kb | Distal (>10kb) Multiome | 98 | |
| chr2:233,251,235–233,252,102 | 375.1 kb | Distal (>10kb) Multiome HiCAR | 955 |
Genomic view of the SNORC locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.