Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC35F2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC35F2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC35F2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:107,565,178–107,566,246 | 293.2 kb | Distal (>10kb) Multiome | 741 | |
| chr11:107,589,994–107,592,189 | 267.5 kb | Distal (>10kb) Multiome | 484 | |
| chr11:107,707,583–107,708,604 | 150.7 kb | Distal (>10kb) Multiome | 189 | |
| chr11:107,833,401–107,834,470 | 24.7 kb | Distal (>10kb) Multiome | 123 | |
| chr11:107,857,895–107,860,083 | 128 bp | At TSS Multiome | 916 | |
| chr11:107,865,842–107,866,125 | 7.1 kb | Proximal (<10kb) | 6 | |
| chr11:107,927,906–107,929,475 | 69.6 kb | Distal (>10kb) Multiome | 653 | |
| chr11:108,008,534–108,009,915 | 150.3 kb | Distal (>10kb) Multiome | 1031 | |
| chr11:108,121,137–108,122,070 | 262.8 kb | Distal (>10kb) Multiome | 878 |
Genomic view of the SLC35F2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.