This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Transcription factors with Perturb-seq knockdown data for SLC25A24. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC25A24 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC25A24, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:107,963,834–107,966,277 | 234.6 kb | Distal (>10kb) Multiome | 524 | |
| chr1:108,082,799–108,083,777 | 117.3 kb | Distal (>10kb) Multiome | 128 | |
| chr1:108,129,664–108,131,170 | 70.1 kb | Distal (>10kb) Multiome | 210 | |
| chr1:108,199,204–108,199,671 | 671 bp | At TSS | 338 | |
| chr1:108,199,776–108,201,075 | 11 bp | At TSS Multiome | 777 | |
| chr1:108,208,944–108,209,512 | 8.6 kb | Proximal (<10kb) | 135 |
Genomic view of the SLC25A24 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.