SLC22A17

solute carrier family 22 member 17 | BOCT, BOIT, NGALR

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in siderophore transport. Located in organelle membrane and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Developmental clusters: GC7

Biological processes 15 terms

intracellular iron ion homeostasis (GO:0006879)membrane (GO:0016020)organelle membrane (GO:0031090)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)protein binding (GO:0005515)siderophore transport (GO:0015891)transmembrane signaling receptor activity (GO:0004888)transmembrane transport (GO:0055085)transmembrane transporter activity (GO:0022857)transmembrane transporter activity (GO:0022857)transmembrane transporter activity (GO:0022857)vacuolar membrane (GO:0005774)

Expression (TPM)

TFs regulating SLC22A17 0 TFs

Transcription factors with Perturb-seq knockdown data for SLC22A17. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC22A17 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to SLC22A17

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC22A17, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr14:23,101,326–23,101,861	251.3 kb	Distal (>10kb) Multiome	83
chr14:23,154,159–23,154,639	198.5 kb	Distal (>10kb) Multiome	392
chr14:23,161,040–23,161,530	191.5 kb	Distal (>10kb) Multiome	397
chr14:23,182,495–23,182,942	170.1 kb	Distal (>10kb) Multiome	139
chr14:23,237,732–23,238,192	115.0 kb	Distal (>10kb) Multiome	536
chr14:23,285,641–23,286,830	66.6 kb	Distal (>10kb) Multiome	962
chr14:23,300,944–23,303,002	51.2 kb	Distal (>10kb) Multiome	1096
chr14:23,306,324–23,307,321	46.1 kb	Distal (>10kb) Multiome	871
chr14:23,320,558–23,322,196	31.7 kb	Distal (>10kb) Multiome HiCAR	1090
chr14:23,346,139–23,346,278	6.6 kb	Proximal (<10kb)	71
chr14:23,346,394–23,346,565	6.3 kb	Proximal (<10kb)	43
chr14:23,351,817–23,353,063	46 bp	At TSS Multiome	403
chr14:23,358,162–23,358,640	5.3 kb	Proximal (<10kb)	31
chr14:23,364,202–23,367,105	13.6 kb	Distal (>10kb) Multiome	353
chr14:23,468,966–23,469,987	116.6 kb	Distal (>10kb) Multiome	955
chr14:23,493,984–23,494,589	141.5 kb	Distal (>10kb) Multiome	131
chr14:23,537,253–23,538,372	184.7 kb	Distal (>10kb) Multiome	160
chr14:23,544,507–23,545,444	191.9 kb	Distal (>10kb) Multiome	308
chr14:23,550,782–23,552,258	198.8 kb	Distal (>10kb) Multiome	826
chr14:23,555,640–23,556,485	203.2 kb	Distal (>10kb) Multiome	983
chr14:23,567,065–23,567,976	214.8 kb	Distal (>10kb) Multiome	855
chr14:23,575,776–23,576,501	223.4 kb	Distal (>10kb) Multiome	163
chr14:23,589,018–23,589,481	236.3 kb	Distal (>10kb) Multiome	770
chr14:23,631,551–23,632,458	279.2 kb	Distal (>10kb) Multiome	545

Genome Browser

Genomic view of the SLC22A17 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.