This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30. [provided by RefSeq, Nov 2016]

Biological processes 51 terms

14-3-3 protein binding (GO:0071889)ATP binding (GO:0005524)ATP binding (GO:0005524)ATP binding (GO:0005524)anoikis (GO:0043276)cAMP response element binding protein binding (GO:0008140)cAMP response element binding protein binding (GO:0008140)cardiac muscle cell differentiation (GO:0055007)cardiac muscle cell differentiation (GO:0055007)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasm (GO:0005737)entrainment of circadian clock by photoperiod (GO:0043153)entrainment of circadian clock by photoperiod (GO:0043153)histone deacetylase binding (GO:0042826)intracellular signal transduction (GO:0035556)intracellular signal transduction (GO:0035556)intracellular signal transduction (GO:0035556)intracellular signal transduction (GO:0035556)magnesium ion binding (GO:0000287)magnesium ion binding (GO:0000287)magnesium ion binding (GO:0000287)negative regulation of gluconeogenesis (GO:0045721)negative regulation of gluconeogenesis (GO:0045721)negative regulation of transcription by RNA polymerase II (GO:0000122)negative regulation of triglyceride biosynthetic process (GO:0010868)negative regulation of triglyceride biosynthetic process (GO:0010868)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)positive regulation of anoikis (GO:2000210)protein autophosphorylation (GO:0046777)protein binding (GO:0005515)protein kinase activity (GO:0004672)protein kinase binding (GO:0019901)protein kinase binding (GO:0019901)protein phosphorylation (GO:0006468)protein phosphorylation (GO:0006468)protein serine kinase activity (GO:0106310)protein serine/threonine kinase activity (GO:0004674)protein serine/threonine kinase activity (GO:0004674)protein serine/threonine kinase activity (GO:0004674)regulation of cell differentiation (GO:0045595)regulation of cell differentiation (GO:0045595)regulation of mitotic cell cycle (GO:0007346)regulation of mitotic cell cycle (GO:0007346)regulation of myotube differentiation (GO:0010830)regulation of myotube differentiation (GO:0010830)regulation of sodium ion transport (GO:0002028)regulation of sodium ion transport (GO:0002028)