Enables enzyme binding activity. Involved in ribosomal small subunit biogenesis. Located in cytosol; nucleolus; and nucleoplasm. Part of small-subunit processome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RPS19BP1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RPS19BP1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RPS19BP1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr22:39,242,211–39,244,345 | 289.9 kb | Distal (>10kb) Multiome | 605 | |
| chr22:39,310,537–39,311,897 | 221.6 kb | Distal (>10kb) Multiome | 655 | |
| chr22:39,319,163–39,320,470 | 213.0 kb | Distal (>10kb) Multiome | 968 | |
| chr22:39,349,608–39,350,646 | 182.9 kb | Distal (>10kb) Multiome | 412 | |
| chr22:39,388,249–39,388,891 | 144.3 kb | Distal (>10kb) Multiome | 336 | |
| chr22:39,399,211–39,400,196 | 133.0 kb | Distal (>10kb) Multiome | 896 | |
| chr22:39,501,766–39,502,757 | 30.5 kb | Distal (>10kb) Multiome | 736 | |
| chr22:39,519,211–39,521,337 | 12.6 kb | Distal (>10kb) Multiome | 1150 | |
| chr22:39,524,998–39,525,864 | 6.9 kb | Proximal (<10kb) | 159 | |
| chr22:39,526,604–39,527,231 | 5.5 kb | Proximal (<10kb) | 127 | |
| chr22:39,528,868–39,529,848 | 3.4 kb | Proximal (<10kb) Multiome | 829 | |
| chr22:39,532,183–39,533,171 | 91 bp | At TSS Multiome | 799 | |
| chr22:39,534,113–39,535,455 | 2.2 kb | Proximal (<10kb) Multiome | 621 | |
| chr22:39,598,010–39,598,521 | 65.6 kb | Distal (>10kb) Multiome | 163 | |
| chr22:39,661,773–39,663,221 | 129.8 kb | Distal (>10kb) Multiome | 260 | |
| chr22:39,663,880–39,665,145 | 131.9 kb | Distal (>10kb) Multiome | 208 | |
| chr22:39,994,434–39,995,793 | 462.1 kb | Distal (>10kb) Multiome HiCAR | 287 | |
| chr22:40,043,949–40,045,800 | 511.8 kb | Distal (>10kb) Multiome HiCAR | 871 | |
| chr22:40,345,883–40,347,047 | 813.8 kb | Distal (>10kb) Multiome HiCAR | 955 | |
| chr22:40,370,270–40,371,111 | 837.9 kb | Distal (>10kb) Multiome HiCAR | 630 | |
| chr22:40,856,149–40,857,393 | 1324.1 kb | Distal (>10kb) Multiome HiCAR | 950 |
Genomic view of the RPS19BP1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.