Enables microtubule binding activity. Located in Golgi apparatus; cytosol; and spindle. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RMDN2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RMDN2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RMDN2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:37,670,970–37,673,170 | 252.7 kb | Distal (>10kb) Multiome | 786 | |
| chr2:37,736,855–37,737,752 | 188.1 kb | Distal (>10kb) Multiome | 124 | |
| chr2:37,924,775–37,925,907 | 133 bp | At TSS Multiome | 1049 | |
| chr2:38,038,070–38,038,591 | 113.1 kb | Distal (>10kb) Multiome | 227 | |
| chr2:38,073,535–38,077,719 | 151.3 kb | Distal (>10kb) Multiome | 747 | |
| chr2:38,095,584–38,097,105 | 170.9 kb | Distal (>10kb) Multiome | 485 |
Genomic view of the RMDN2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.