Predicted to enable RNA binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RBM18. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RBM18 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RBM18, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:122,092,682–122,093,762 | 171.5 kb | Distal (>10kb) Multiome | 771 | |
| chr9:122,099,169–122,100,386 | 165.1 kb | Distal (>10kb) Multiome | 262 | |
| chr9:122,159,157–122,160,157 | 105.0 kb | Distal (>10kb) Multiome | 592 | |
| chr9:122,213,553–122,214,655 | 50.7 kb | Distal (>10kb) Multiome | 629 | |
| chr9:122,219,092–122,220,535 | 45.3 kb | Distal (>10kb) Multiome | 158 | |
| chr9:122,228,256–122,229,326 | 36.0 kb | Distal (>10kb) Multiome | 307 | |
| chr9:122,264,447–122,265,544 | 4 bp | At TSS Multiome | 1042 | |
| chr9:122,405,953–122,406,784 | 141.5 kb | Distal (>10kb) Multiome | 118 | |
| chr9:122,562,159–122,562,684 | 297.5 kb | Distal (>10kb) Multiome | 32 |
Genomic view of the RBM18 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.