Predicted to enable GTP binding activity and GTPase activity. Involved in Golgi organization. Located in Golgi cisterna; cis-Golgi network; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for RAB30. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RAB30 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RAB30, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:82,775,808–82,776,868 | 295.7 kb | Distal (>10kb) Multiome | 252 | |
| chr11:82,899,722–82,902,187 | 170.2 kb | Distal (>10kb) Multiome HiCAR | 1001 | |
| chr11:82,970,431–82,971,628 | 101.0 kb | Distal (>10kb) Multiome | 188 | |
| chr11:83,034,012–83,034,897 | 37.3 kb | Distal (>10kb) Multiome | 343 | |
| chr11:83,070,440–83,070,621 | 1.2 kb | Proximal (<10kb) | 119 | |
| chr11:83,071,319–83,072,558 | 131 bp | At TSS Multiome | 943 | |
| chr11:83,144,373–83,145,287 | 73.0 kb | Distal (>10kb) Multiome | 76 | |
| chr11:83,156,155–83,158,430 | 85.1 kb | Distal (>10kb) Multiome | 1001 | |
| chr11:83,193,357–83,194,770 | 121.9 kb | Distal (>10kb) Multiome | 817 | |
| chr11:83,241,143–83,241,871 | 169.7 kb | Distal (>10kb) Multiome | 285 | |
| chr11:83,285,491–83,286,808 | 214.4 kb | Distal (>10kb) Multiome | 1057 | |
| chr11:83,318,271–83,319,586 | 247.1 kb | Distal (>10kb) Multiome | 190 |
Genomic view of the RAB30 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.