Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be involved in epithelial structure maintenance. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for PRRC1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = PRRC1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of PRRC1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:126,674,036–126,674,611 | 843.3 kb | Distal (>10kb) Multiome HiCAR | 99 | |
| chr5:127,228,773–127,229,922 | 288.2 kb | Distal (>10kb) Multiome | 517 | |
| chr5:127,289,796–127,291,714 | 227.1 kb | Distal (>10kb) Multiome HiCAR | 438 | |
| chr5:127,324,468–127,325,160 | 192.8 kb | Distal (>10kb) Multiome | 115 | |
| chr5:127,517,064–127,518,431 | 6 bp | At TSS Multiome | 880 | |
| chr5:128,536,194–128,539,650 | 1020.8 kb | Distal (>10kb) Multiome HiCAR | 630 |
Genomic view of the PRRC1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.