Predicted to enable oxidoreductase activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for OXNAD1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = OXNAD1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of OXNAD1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:16,255,797–16,256,291 | 8.9 kb | Proximal (<10kb) | 86 | |
| chr3:16,264,456–16,265,625 | 151 bp | At TSS Multiome | 886 | |
| chr3:16,302,010–16,302,566 | 37.1 kb | Distal (>10kb) Multiome | 117 | |
| chr3:16,482,708–16,483,517 | 218.0 kb | Distal (>10kb) Multiome | 376 |
Genomic view of the OXNAD1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.