MFSD3

solute carrier family 33 member 2 | MFSD3

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-1

Biological processes 8 terms

membrane (GO:0016020)membrane (GO:0016020)plasma membrane (GO:0005886)plasma membrane (GO:0005886)protein binding (GO:0005515)transmembrane transport (GO:0055085)transmembrane transporter activity (GO:0022857)transmembrane transporter activity (GO:0022857)

Expression (TPM)

TFs regulating MFSD3 0 TFs

Transcription factors with Perturb-seq knockdown data for MFSD3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MFSD3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to MFSD3

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MFSD3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr8:144,266,293–144,267,098	242.6 kb	Distal (>10kb) Multiome	162
chr8:144,290,981–144,292,410	217.6 kb	Distal (>10kb) Multiome	716
chr8:144,315,833–144,316,450	192.9 kb	Distal (>10kb) Multiome	396
chr8:144,325,768–144,327,719	182.2 kb	Distal (>10kb) Multiome	1016
chr8:144,331,281–144,333,847	177.1 kb	Distal (>10kb) Multiome	406
chr8:144,336,102–144,339,119	172.2 kb	Distal (>10kb) Multiome	922
chr8:144,353,907–144,355,227	154.5 kb	Distal (>10kb) Multiome	280
chr8:144,358,142–144,359,070	150.5 kb	Distal (>10kb) Multiome	719
chr8:144,369,349–144,369,916	139.4 kb	Distal (>10kb) Multiome	204
chr8:144,372,497–144,372,883	136.4 kb	Distal (>10kb) Multiome	160
chr8:144,372,993–144,375,084	135.1 kb	Distal (>10kb) Multiome	903
chr8:144,408,968–144,410,189	99.6 kb	Distal (>10kb) Multiome	920
chr8:144,427,691–144,429,571	80.5 kb	Distal (>10kb) Multiome	1000
chr8:144,443,691–144,445,047	64.7 kb	Distal (>10kb) Multiome	743
chr8:144,462,568–144,463,422	46.2 kb	Distal (>10kb) Multiome HiCAR	548
chr8:144,463,885–144,468,178	43.3 kb	Distal (>10kb) Multiome HiCAR	910
chr8:144,471,960–144,474,391	36.5 kb	Distal (>10kb) Multiome HiCAR	482
chr8:144,474,517–144,476,543	33.2 kb	Distal (>10kb) Multiome HiCAR	321
chr8:144,477,277–144,478,749	31.1 kb	Distal (>10kb) Multiome HiCAR	679
chr8:144,478,851–144,479,509	29.8 kb	Distal (>10kb) Multiome HiCAR	392
chr8:144,483,979–144,484,843	24.7 kb	Distal (>10kb) Multiome	125
chr8:144,495,748–144,496,431	13.0 kb	Distal (>10kb) Multiome	131
chr8:144,500,182–144,501,505	8.1 kb	Proximal (<10kb) Multiome	484
chr8:144,507,995–144,510,268	202 bp	At TSS Multiome	1067
chr8:144,512,021–144,512,229	3.0 kb	Proximal (<10kb)	89
chr8:144,517,168–144,518,442	8.8 kb	Proximal (<10kb) Multiome	637
chr8:144,521,935–144,523,450	13.4 kb	Distal (>10kb) Multiome	663
chr8:144,524,105–144,525,099	15.6 kb	Distal (>10kb) Multiome	264
chr8:144,526,399–144,529,305	18.0 kb	Distal (>10kb) Multiome	934
chr8:144,529,455–144,530,630	21.1 kb	Distal (>10kb) Multiome	284
chr8:144,580,290–144,581,657	71.7 kb	Distal (>10kb) Multiome	271
chr8:144,672,507–144,672,989	163.8 kb	Distal (>10kb) Multiome	150
chr8:144,684,108–144,686,340	175.3 kb	Distal (>10kb) Multiome	862
chr8:144,755,078–144,755,956	246.5 kb	Distal (>10kb) Multiome	769
chr8:144,785,987–144,788,592	278.1 kb	Distal (>10kb) Multiome	997
chr8:144,791,751–144,793,221	283.4 kb	Distal (>10kb) Multiome	899
chr8:144,798,389–144,799,501	289.8 kb	Distal (>10kb) Multiome	832

Genome Browser

Genomic view of the MFSD3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.