MCRIP2
MAPK regulated corepressor interacting protein 2 | MGC15416, C16orf14, FAM195A
MCRIP2 — as a Regulated Gene

TFs regulating MCRIP2 0 TFs

Transcription factors with Perturb-seq knockdown data for MCRIP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MCRIP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to MCRIP2

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MCRIP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr16:351,804–354,436 289.0 kb Distal (>10kb) Multiome 654
chr16:378,999–379,813 262.6 kb Distal (>10kb) Multiome 225
chr16:380,836–382,614 260.0 kb Distal (>10kb) Multiome 634
chr16:383,438–384,218 258.1 kb Distal (>10kb) Multiome 342
chr16:396,893–397,640 244.4 kb Distal (>10kb) Multiome 496
chr16:401,380–402,199 240.1 kb Distal (>10kb) Multiome 818
chr16:424,888–426,136 216.3 kb Distal (>10kb) Multiome 752
chr16:483,333–484,000 158.2 kb Distal (>10kb) Multiome 143
chr16:526,749–528,601 114.3 kb Distal (>10kb) Multiome 811
chr16:569,530–570,338 72.1 kb Distal (>10kb) Multiome 492
chr16:578,896–579,353 62.8 kb Distal (>10kb) Multiome 511
chr16:588,593–590,724 52.1 kb Distal (>10kb) Multiome 853
chr16:635,900–638,127 5.6 kb Proximal (<10kb) Multiome 1021
chr16:641,491–643,007 61 bp At TSS Multiome 856
chr16:648,795–649,829 7.4 kb Proximal (<10kb) Multiome 862
chr16:660,457–661,656 19.0 kb Distal (>10kb) Multiome 456
chr16:667,633–668,442 26.1 kb Distal (>10kb) Multiome 838
chr16:678,847–681,585 38.1 kb Distal (>10kb) Multiome 803
chr16:683,618–684,859 42.5 kb Distal (>10kb) Multiome 701
chr16:694,897–695,485 53.5 kb Distal (>10kb) Multiome 390
chr16:705,242–706,468 64.0 kb Distal (>10kb) Multiome 248
chr16:714,577–716,048 73.2 kb Distal (>10kb) Multiome 555
chr16:720,434–721,963 79.4 kb Distal (>10kb) Multiome 966
chr16:726,310–729,144 85.1 kb Distal (>10kb) Multiome 736
chr16:740,359–741,596 99.2 kb Distal (>10kb) Multiome 897
chr16:787,564–789,160 146.6 kb Distal (>10kb) Multiome 635
chr16:807,352–808,044 165.9 kb Distal (>10kb) Multiome 600
chr16:813,330–813,960 171.9 kb Distal (>10kb) Multiome 325

Genome Browser

Genomic view of the MCRIP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr16:341,804 – 823,960
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq