Transcription factors with Perturb-seq knockdown data for LINC02482. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = LINC02482 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of LINC02482, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr4:6,470,551–6,471,324 | 203.0 kb | Distal (>10kb) Multiome | 373 | |
| chr4:6,472,122–6,472,949 | 201.4 kb | Distal (>10kb) Multiome | 157 | |
| chr4:6,574,723–6,575,464 | 98.9 kb | Distal (>10kb) Multiome | 601 | |
| chr4:6,640,089–6,641,132 | 33.4 kb | Distal (>10kb) Multiome | 851 | |
| chr4:6,673,157–6,674,688 | 38 bp | At TSS Multiome | 920 | |
| chr4:6,709,388–6,710,099 | 35.9 kb | Distal (>10kb) Multiome | 693 | |
| chr4:6,715,775–6,716,910 | 42.2 kb | Distal (>10kb) Multiome | 822 | |
| chr4:6,782,106–6,784,027 | 108.6 kb | Distal (>10kb) Multiome | 886 | |
| chr4:6,908,950–6,910,715 | 235.7 kb | Distal (>10kb) Multiome | 820 |
Genomic view of the LINC02482 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.