Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for LINC00869. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = LINC00869 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of LINC00869, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:149,390,297–149,390,919 | 216.8 kb | Distal (>10kb) Multiome | 253 | |
| chr1:149,607,914–149,608,032 | 608 bp | At TSS | 38 | |
| chr1:149,636,175–149,637,106 | 29.2 kb | Distal (>10kb) Multiome | 687 | |
| chr1:149,812,136–149,812,633 | 205.1 kb | Distal (>10kb) Multiome | 190 | |
| chr1:149,885,029–149,889,131 | 281.0 kb | Distal (>10kb) Multiome | 1126 | |
| chr1:149,899,425–149,900,227 | 292.4 kb | Distal (>10kb) Multiome | 650 |
Genomic view of the LINC00869 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.