Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for INAFM1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = INAFM1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of INAFM1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:47,019,502–47,020,076 | 255.2 kb | Distal (>10kb) Multiome | 188 | |
| chr19:47,035,599–47,036,293 | 238.9 kb | Distal (>10kb) Multiome | 627 | |
| chr19:47,047,837–47,048,980 | 227.0 kb | Distal (>10kb) Multiome | 760 | |
| chr19:47,058,561–47,059,308 | 216.0 kb | Distal (>10kb) Multiome | 357 | |
| chr19:47,111,821–47,113,936 | 162.7 kb | Distal (>10kb) Multiome | 1117 | |
| chr19:47,130,439–47,131,651 | 144.1 kb | Distal (>10kb) Multiome | 908 | |
| chr19:47,157,325–47,158,494 | 117.3 kb | Distal (>10kb) Multiome | 271 | |
| chr19:47,196,586–47,197,452 | 78.0 kb | Distal (>10kb) Multiome | 94 | |
| chr19:47,225,386–47,231,990 | 47.1 kb | Distal (>10kb) Multiome | 1389 | |
| chr19:47,240,827–47,241,572 | 33.7 kb | Distal (>10kb) Multiome | 616 | |
| chr19:47,242,713–47,243,645 | 31.8 kb | Distal (>10kb) Multiome | 568 | |
| chr19:47,243,835–47,244,896 | 30.5 kb | Distal (>10kb) Multiome | 1001 | |
| chr19:47,256,041–47,258,057 | 17.8 kb | Distal (>10kb) Multiome | 907 | |
| chr19:47,272,778–47,275,890 | 1.5 kb | Proximal (<10kb) Multiome | 931 | |
| chr19:47,348,695–47,349,758 | 74.3 kb | Distal (>10kb) Multiome | 766 | |
| chr19:47,406,825–47,407,408 | 132.4 kb | Distal (>10kb) Multiome | 333 | |
| chr19:47,427,132–47,428,809 | 152.4 kb | Distal (>10kb) Multiome | 506 | |
| chr19:47,429,865–47,430,531 | 155.4 kb | Distal (>10kb) Multiome | 438 | |
| chr19:47,447,043–47,448,262 | 172.8 kb | Distal (>10kb) Multiome | 510 | |
| chr19:47,471,631–47,472,340 | 197.1 kb | Distal (>10kb) Multiome | 500 | |
| chr19:47,483,636–47,484,543 | 209.3 kb | Distal (>10kb) Multiome | 841 | |
| chr19:47,514,152–47,515,901 | 240.4 kb | Distal (>10kb) Multiome | 895 |
Genomic view of the INAFM1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.