IFFO2
intermediate filament family orphan 2

Predicted to be located in intermediate filament. [provided by Alliance of Genome Resources, Jul 2025]

Developmental clusters: GC4
Expression (TPM)
IFFO2 — as a Regulated Gene

TFs regulating IFFO2 0 TFs

Transcription factors with Perturb-seq knockdown data for IFFO2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = IFFO2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to IFFO2

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of IFFO2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr1:18,955,480–18,957,564 at TSS At TSS 702

Genome Browser

Genomic view of the IFFO2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr1:18,945,480 – 18,967,564
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq