Enables fucosyltransferase activity. Involved in N-glycan fucosylation. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for FUT10. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FUT10 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FUT10, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:33,187,460–33,188,474 | 285.1 kb | Distal (>10kb) Multiome | 176 | |
| chr8:33,223,201–33,224,129 | 249.5 kb | Distal (>10kb) Multiome | 103 | |
| chr8:33,471,825–33,473,740 | 60 bp | At TSS Multiome | 999 | |
| chr8:33,484,346–33,485,645 | 11.9 kb | Distal (>10kb) Multiome | 940 | |
| chr8:33,512,345–33,515,139 | 41.6 kb | Distal (>10kb) Multiome | 1310 | |
| chr8:33,543,087–33,543,854 | 70.3 kb | Distal (>10kb) Multiome | 102 | |
| chr8:33,566,077–33,567,716 | 94.0 kb | Distal (>10kb) Multiome | 711 | |
| chr8:33,626,086–33,627,037 | 153.3 kb | Distal (>10kb) Multiome | 118 |
Genomic view of the FUT10 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.