Enables RNA binding activity. Predicted to be involved in spermatid development. Predicted to act upstream of or within Sertoli cell development; cell-cell adhesion; and fertilization. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FNDC3A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FNDC3A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FNDC3A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr13:48,876,214–48,877,055 | 99.3 kb | Distal (>10kb) Multiome | 225 | |
| chr13:48,975,109–48,976,919 | 566 bp | At TSS Multiome | 933 | |
| chr13:49,110,170–49,110,390 | at TSS | At TSS | 505 | |
| chr13:49,184,188–49,185,149 | 208.9 kb | Distal (>10kb) Multiome | 84 | |
| chr13:49,218,368–49,219,071 | 242.8 kb | Distal (>10kb) Multiome | 51 | |
| chr13:49,219,748–49,221,361 | 244.3 kb | Distal (>10kb) Multiome | 441 | |
| chr13:49,247,525–49,248,779 | 272.0 kb | Distal (>10kb) Multiome | 752 | |
| chr13:49,280,990–49,281,662 | 305.4 kb | Distal (>10kb) Multiome | 111 |
Genomic view of the FNDC3A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.