Involved in protein localization to perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FHIP1A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FHIP1A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FHIP1A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr4:151,324,320–151,326,042 | 84.6 kb | Distal (>10kb) Multiome | 942 | |
| chr4:151,407,549–151,410,460 | 158 bp | At TSS Multiome | 800 | |
| chr4:151,488,949–151,490,034 | 80.5 kb | Distal (>10kb) Multiome | 186 | |
| chr4:151,637,197–151,637,951 | 228.4 kb | Distal (>10kb) Multiome HiCAR | 96 | |
| chr4:151,639,607–151,640,861 | 231.2 kb | Distal (>10kb) Multiome HiCAR | 93 |
Genomic view of the FHIP1A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.