Predicted to enable identical protein binding activity. Predicted to be involved in response to wounding. Predicted to act upstream of or within wound healing. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FGFR1OP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FGFR1OP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FGFR1OP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:26,679,082–26,679,573 | 259.2 kb | Distal (>10kb) Multiome | 121 | |
| chr12:26,831,973–26,834,292 | 105.1 kb | Distal (>10kb) Multiome | 945 | |
| chr12:26,884,786–26,885,430 | 53.5 kb | Distal (>10kb) Multiome | 412 | |
| chr12:26,937,248–26,939,182 | 188 bp | At TSS Multiome | 853 | |
| chr12:27,013,686–27,014,988 | 75.9 kb | Distal (>10kb) Multiome | 864 | |
| chr12:27,021,899–27,022,924 | 84.0 kb | Distal (>10kb) Multiome | 783 |
Genomic view of the FGFR1OP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.