Enables phosphotransferase activity, alcohol group as acceptor. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FAM20B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAM20B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAM20B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:178,541,715–178,543,543 | 483.1 kb | Distal (>10kb) Multiome HiCAR | 856 | |
| chr1:178,724,480–178,726,551 | 299.5 kb | Distal (>10kb) Multiome | 861 | |
| chr1:179,002,311–179,003,353 | 23.1 kb | Distal (>10kb) Multiome | 522 | |
| chr1:179,025,292–179,027,102 | 84 bp | At TSS Multiome | 930 | |
| chr1:179,081,467–179,083,301 | 56.1 kb | Distal (>10kb) Multiome | 968 | |
| chr1:179,087,385–179,088,206 | 61.9 kb | Distal (>10kb) Multiome | 194 | |
| chr1:179,228,751–179,230,142 | 203.8 kb | Distal (>10kb) Multiome | 634 | |
| chr1:179,293,131–179,294,199 | 267.9 kb | Distal (>10kb) Multiome | 884 |
Genomic view of the FAM20B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.