Enables mannosyltransferase activity. Predicted to be involved in protein glycosylation. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for DPY19L3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DPY19L3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DPY19L3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:32,345,298–32,346,342 | 60.1 kb | Distal (>10kb) Multiome | 791 | |
| chr19:32,403,163–32,403,921 | 2.3 kb | Proximal (<10kb) Multiome | 151 | |
| chr19:32,405,092–32,406,553 | 18 bp | At TSS Multiome | 914 | |
| chr19:32,580,669–32,581,896 | 175.4 kb | Distal (>10kb) Multiome | 774 | |
| chr19:32,674,338–32,676,683 | 269.5 kb | Distal (>10kb) Multiome | 792 | |
| chr19:32,691,659–32,692,482 | 286.2 kb | Distal (>10kb) Multiome | 839 | |
| chr19:32,701,845–32,702,627 | 296.5 kb | Distal (>10kb) Multiome | 257 |
Genomic view of the DPY19L3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.