Predicted to enable mannosyltransferase activity. Predicted to be involved in protein glycosylation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for DPY19L1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DPY19L1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DPY19L1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:34,831,901–34,832,506 | 205.9 kb | Distal (>10kb) Multiome HiCAR | 99 | |
| chr7:35,035,502–35,036,122 | 1.9 kb | Proximal (<10kb) | 204 | |
| chr7:35,036,664–35,038,744 | 310 bp | At TSS Multiome | 804 | |
| chr7:35,185,645–35,187,217 | 148.2 kb | Distal (>10kb) Multiome | 274 | |
| chr7:35,248,647–35,249,942 | 211.1 kb | Distal (>10kb) Multiome | 358 | |
| chr7:35,253,386–35,255,107 | 216.1 kb | Distal (>10kb) Multiome | 357 | |
| chr7:35,261,015–35,262,351 | 223.9 kb | Distal (>10kb) Multiome | 217 | |
| chr7:35,301,809–35,303,376 | 264.4 kb | Distal (>10kb) Multiome | 85 | |
| chr7:35,331,849–35,332,680 | 294.1 kb | Distal (>10kb) Multiome | 175 | |
| chr7:35,537,034–35,537,920 | 499.5 kb | Distal (>10kb) Multiome HiCAR | 411 |
Genomic view of the DPY19L1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.