Predicted to enable dopamine receptor binding activity. Predicted to be involved in protein transport. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for DNAJC14. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DNAJC14 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DNAJC14, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:55,630,484–55,631,684 | 198.5 kb | Distal (>10kb) Multiome | 41 | |
| chr12:55,645,990–55,646,787 | 183.2 kb | Distal (>10kb) Multiome | 520 | |
| chr12:55,681,171–55,682,136 | 148.0 kb | Distal (>10kb) Multiome | 647 | |
| chr12:55,707,276–55,708,500 | 121.6 kb | Distal (>10kb) Multiome | 372 | |
| chr12:55,715,733–55,716,775 | 113.3 kb | Distal (>10kb) Multiome | 929 | |
| chr12:55,727,952–55,730,453 | 99.9 kb | Distal (>10kb) Multiome | 895 | |
| chr12:55,736,969–55,737,781 | 92.3 kb | Distal (>10kb) Multiome HiCAR | 496 | |
| chr12:55,737,830–55,739,085 | 91.0 kb | Distal (>10kb) Multiome HiCAR | 475 | |
| chr12:55,742,540–55,744,252 | 86.4 kb | Distal (>10kb) Multiome HiCAR | 631 | |
| chr12:55,745,091–55,746,361 | 83.8 kb | Distal (>10kb) Multiome HiCAR | 299 | |
| chr12:55,817,254–55,818,558 | 11.7 kb | Distal (>10kb) Multiome | 749 | |
| chr12:55,829,008–55,831,505 | 49 bp | At TSS Multiome | 921 | |
| chr12:55,926,651–55,928,471 | 97.4 kb | Distal (>10kb) Multiome HiCAR | 993 | |
| chr12:55,931,904–55,932,439 | 102.5 kb | Distal (>10kb) Multiome | 279 | |
| chr12:55,940,073–55,940,746 | 110.8 kb | Distal (>10kb) Multiome HiCAR | 478 | |
| chr12:55,966,006–55,967,470 | 137.1 kb | Distal (>10kb) Multiome | 615 | |
| chr12:55,973,347–55,974,716 | 144.3 kb | Distal (>10kb) Multiome | 966 | |
| chr12:55,996,814–55,997,861 | 167.6 kb | Distal (>10kb) Multiome | 680 | |
| chr12:56,006,888–56,008,461 | 178.0 kb | Distal (>10kb) Multiome | 745 | |
| chr12:56,020,644–56,021,511 | 191.4 kb | Distal (>10kb) Multiome | 364 | |
| chr12:56,041,220–56,042,537 | 212.2 kb | Distal (>10kb) Multiome | 1035 | |
| chr12:56,078,964–56,081,015 | 249.6 kb | Distal (>10kb) Multiome | 1032 | |
| chr12:56,103,918–56,105,302 | 274.8 kb | Distal (>10kb) Multiome | 977 | |
| chr12:56,115,844–56,117,060 | 286.9 kb | Distal (>10kb) Multiome | 958 | |
| chr12:56,117,641–56,119,301 | 288.6 kb | Distal (>10kb) Multiome | 1052 | |
| chr12:56,126,181–56,126,640 | 296.7 kb | Distal (>10kb) Multiome | 671 | |
| chr12:56,127,552–56,129,104 | 298.5 kb | Distal (>10kb) Multiome | 800 |
Genomic view of the DNAJC14 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.