CYB5D1
cytochrome b5 domain containing 1 | FLJ32499

Predicted to enable metal ion binding activity. Predicted to be involved in cilium movement and regulation of cilium beat frequency. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 9 terms
Expression (TPM)
CYB5D1 — as a Regulated Gene

TFs regulating CYB5D1 0 TFs

Transcription factors with Perturb-seq knockdown data for CYB5D1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CYB5D1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to CYB5D1

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CYB5D1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr17:7,560,249–7,562,536 295.8 kb Distal (>10kb) Multiome 759
chr17:7,572,039–7,574,418 285.1 kb Distal (>10kb) Multiome 1071
chr17:7,579,018–7,579,876 278.3 kb Distal (>10kb) Multiome 844
chr17:7,583,063–7,584,547 274.0 kb Distal (>10kb) Multiome 921
chr17:7,588,871–7,590,534 267.5 kb Distal (>10kb) Multiome 319
chr17:7,614,065–7,615,780 242.6 kb Distal (>10kb) Multiome 708
chr17:7,627,090–7,628,247 229.9 kb Distal (>10kb) Multiome 712
chr17:7,650,010–7,652,127 207.0 kb Distal (>10kb) Multiome 467
chr17:7,685,876–7,686,907 171.5 kb Distal (>10kb) Multiome 765
chr17:7,687,214–7,687,777 170.2 kb Distal (>10kb) Multiome 710
chr17:7,687,867–7,688,863 169.4 kb Distal (>10kb) Multiome 700
chr17:7,703,383–7,703,975 154.1 kb Distal (>10kb) Multiome 141
chr17:7,704,799–7,705,590 152.6 kb Distal (>10kb) Multiome 325
chr17:7,716,832–7,717,983 140.4 kb Distal (>10kb) Multiome 759
chr17:7,833,417–7,837,960 20.7 kb Distal (>10kb) Multiome 1160
chr17:7,841,438–7,843,228 15.5 kb Distal (>10kb) Multiome 861
chr17:7,843,355–7,844,130 14.1 kb Distal (>10kb) Multiome 614
chr17:7,844,349–7,845,186 12.8 kb Distal (>10kb) Multiome 617
chr17:7,851,538–7,852,239 5.9 kb Proximal (<10kb) Multiome 531
chr17:7,853,062–7,853,638 4.1 kb Proximal (<10kb) 99
chr17:7,854,798–7,855,188 2.6 kb Proximal (<10kb) 106
chr17:7,856,600–7,858,747 231 bp At TSS Multiome 942
chr17:7,887,616–7,888,198 30.1 kb Distal (>10kb) Multiome 581
chr17:7,915,430–7,916,499 58.2 kb Distal (>10kb) Multiome 869
chr17:7,922,863–7,923,421 65.3 kb Distal (>10kb) Multiome 205
chr17:7,929,559–7,930,172 72.1 kb Distal (>10kb) Multiome 106
chr17:7,931,533–7,932,876 74.4 kb Distal (>10kb) Multiome 767
chr17:7,989,908–7,990,676 132.5 kb Distal (>10kb) Multiome 652
chr17:8,015,966–8,016,968 159.0 kb Distal (>10kb) Multiome 339
chr17:8,079,261–8,080,640 222.4 kb Distal (>10kb) Multiome 613
chr17:8,109,567–8,110,530 252.6 kb Distal (>10kb) Multiome 360
chr17:8,117,780–8,119,396 261.2 kb Distal (>10kb) Multiome 684
chr17:8,119,590–8,122,560 262.9 kb Distal (>10kb) Multiome 968
chr17:8,123,407–8,124,386 266.4 kb Distal (>10kb) Multiome 296
chr17:8,125,308–8,126,995 268.0 kb Distal (>10kb) Multiome 724
chr17:8,138,425–8,139,804 281.3 kb Distal (>10kb) Multiome 981
chr17:8,151,914–8,152,786 294.8 kb Distal (>10kb) Multiome 633
chr17:8,153,878–8,154,864 296.6 kb Distal (>10kb) Multiome 644
chr17:8,155,928–8,157,418 298.9 kb Distal (>10kb) Multiome 789

Genome Browser

Genomic view of the CYB5D1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr17:7,550,249 – 8,167,418
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq