Located in cell surface. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CLDND1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CLDND1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CLDND1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:98,514,790–98,515,181 | 7.7 kb | Proximal (<10kb) | 23 | |
| chr3:98,521,861–98,523,430 | 10 bp | At TSS Multiome | 832 | |
| chr3:98,528,480–98,528,902 | 5.6 kb | Proximal (<10kb) | 116 | |
| chr3:98,532,271–98,533,110 | 9.4 kb | Proximal (<10kb) | 85 | |
| chr3:98,592,698–98,594,265 | 70.8 kb | Distal (>10kb) Multiome | 864 | |
| chr3:98,732,084–98,734,092 | 209.6 kb | Distal (>10kb) Multiome | 726 |
Genomic view of the CLDND1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.