Enables oligosaccharide binding activity. Involved in negative regulation of cytokine production involved in inflammatory response. Located in several cellular components, including late endosome; lysosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CHID1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CHID1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CHID1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:613,334–614,059 | 297.1 kb | Distal (>10kb) Multiome | 215 | |
| chr11:615,262–616,320 | 294.9 kb | Distal (>10kb) Multiome | 443 | |
| chr11:636,786–637,700 | 273.7 kb | Distal (>10kb) Multiome | 161 | |
| chr11:693,835–696,330 | 215.4 kb | Distal (>10kb) Multiome | 873 | |
| chr11:705,737–706,270 | 204.8 kb | Distal (>10kb) Multiome | 361 | |
| chr11:720,619–721,074 | 189.9 kb | Distal (>10kb) Multiome | 156 | |
| chr11:727,901–728,499 | 182.6 kb | Distal (>10kb) Multiome | 686 | |
| chr11:746,704–748,069 | 163.5 kb | Distal (>10kb) Multiome | 755 | |
| chr11:762,582–763,602 | 147.5 kb | Distal (>10kb) Multiome | 326 | |
| chr11:776,216–778,328 | 133.4 kb | Distal (>10kb) Multiome | 770 | |
| chr11:783,385–783,909 | 127.1 kb | Distal (>10kb) Multiome | 278 | |
| chr11:797,112–798,675 | 112.6 kb | Distal (>10kb) Multiome | 697 | |
| chr11:804,241–805,812 | 105.5 kb | Distal (>10kb) Multiome | 725 | |
| chr11:808,894–810,402 | 101.1 kb | Distal (>10kb) Multiome | 976 | |
| chr11:818,369–820,592 | 91.3 kb | Distal (>10kb) Multiome | 749 | |
| chr11:826,980–828,116 | 83.3 kb | Distal (>10kb) Multiome | 662 | |
| chr11:828,933–831,262 | 80.4 kb | Distal (>10kb) Multiome | 491 | |
| chr11:832,323–833,565 | 77.9 kb | Distal (>10kb) Multiome | 562 | |
| chr11:842,034–843,556 | 68.1 kb | Distal (>10kb) Multiome | 794 | |
| chr11:843,773–845,220 | 66.4 kb | Distal (>10kb) Multiome | 664 | |
| chr11:849,082–850,270 | 61.0 kb | Distal (>10kb) Multiome | 229 | |
| chr11:910,337–911,591 | 149 bp | At TSS Multiome | 754 | |
| chr11:925,038–926,264 | 15.0 kb | Distal (>10kb) Multiome | 689 |
Genomic view of the CHID1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.