Predicted to be involved in flagellated sperm motility. Located in axoneme and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CFAP68. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CFAP68 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CFAP68, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:111,601,692–111,603,359 | 277.2 kb | Distal (>10kb) Multiome | 853 | |
| chr11:111,765,276–111,766,937 | 113.1 kb | Distal (>10kb) Multiome | 726 | |
| chr11:111,784,858–111,785,661 | 94.3 kb | Distal (>10kb) Multiome | 164 | |
| chr11:111,870,839–111,871,692 | 8.3 kb | Proximal (<10kb) Multiome | 781 | |
| chr11:111,878,459–111,879,798 | 380 bp | At TSS Multiome | 970 | |
| chr11:111,918,534–111,919,259 | 39.4 kb | Distal (>10kb) Multiome | 468 | |
| chr11:111,926,372–111,927,689 | 47.6 kb | Distal (>10kb) Multiome | 767 | |
| chr11:111,936,752–111,938,016 | 57.7 kb | Distal (>10kb) Multiome | 671 | |
| chr11:111,960,703–111,961,374 | 81.5 kb | Distal (>10kb) Multiome | 192 | |
| chr11:111,976,357–111,978,029 | 97.7 kb | Distal (>10kb) Multiome HiCAR | 293 | |
| chr11:111,982,641–111,983,482 | 103.8 kb | Distal (>10kb) Multiome HiCAR | 290 | |
| chr11:112,024,495–112,025,893 | 145.6 kb | Distal (>10kb) Multiome | 1024 | |
| chr11:112,073,749–112,074,754 | 194.7 kb | Distal (>10kb) Multiome | 828 | |
| chr11:112,086,268–112,087,320 | 207.2 kb | Distal (>10kb) Multiome | 883 |
Genomic view of the CFAP68 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.