Enables identical protein binding activity. Acts upstream of or within cell adhesion. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CERCAM. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CERCAM upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CERCAM, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:128,127,314–128,128,793 | 292.6 kb | Distal (>10kb) Multiome | 899 | |
| chr9:128,159,371–128,160,928 | 260.7 kb | Distal (>10kb) Multiome | 824 | |
| chr9:128,191,300–128,192,050 | 229.2 kb | Distal (>10kb) Multiome | 865 | |
| chr9:128,203,004–128,204,704 | 216.5 kb | Distal (>10kb) Multiome | 690 | |
| chr9:128,250,012–128,251,099 | 170.3 kb | Distal (>10kb) Multiome | 353 | |
| chr9:128,275,636–128,276,535 | 144.8 kb | Distal (>10kb) Multiome | 728 | |
| chr9:128,322,183–128,322,933 | 98.3 kb | Distal (>10kb) Multiome | 962 | |
| chr9:128,340,070–128,341,161 | 80.4 kb | Distal (>10kb) Multiome | 803 | |
| chr9:128,364,858–128,365,437 | 55.7 kb | Distal (>10kb) Multiome | 442 | |
| chr9:128,412,493–128,412,685 | 8.2 kb | Proximal (<10kb) | 236 | |
| chr9:128,420,259–128,421,260 | 122 bp | At TSS Multiome | 701 | |
| chr9:128,455,721–128,456,522 | 35.2 kb | Distal (>10kb) Multiome | 684 | |
| chr9:128,504,482–128,505,188 | 83.9 kb | Distal (>10kb) Multiome | 766 | |
| chr9:128,552,006–128,553,125 | 131.6 kb | Distal (>10kb) Multiome | 839 | |
| chr9:128,656,436–128,657,126 | 236.0 kb | Distal (>10kb) Multiome | 1009 | |
| chr9:128,683,393–128,684,010 | 262.8 kb | Distal (>10kb) Multiome | 296 | |
| chr9:128,684,170–128,684,813 | 263.9 kb | Distal (>10kb) Multiome | 574 | |
| chr9:128,688,449–128,689,713 | 268.2 kb | Distal (>10kb) Multiome | 805 | |
| chr9:128,702,246–128,702,946 | 281.7 kb | Distal (>10kb) Multiome | 720 |
Genomic view of the CERCAM locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.