Involved in cilium assembly. Located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CEP162. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CEP162 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CEP162, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:83,707,656–83,709,786 | 518.5 kb | Distal (>10kb) Multiome HiCAR | 496 | |
| chr6:83,852,941–83,854,471 | 374.1 kb | Distal (>10kb) Multiome HiCAR | 497 | |
| chr6:83,859,075–83,860,410 | 368.0 kb | Distal (>10kb) Multiome HiCAR | 1062 | |
| chr6:84,033,204–84,034,688 | 193.8 kb | Distal (>10kb) Multiome | 473 | |
| chr6:84,052,161–84,053,196 | 175.0 kb | Distal (>10kb) Multiome | 417 | |
| chr6:84,086,644–84,088,326 | 140.3 kb | Distal (>10kb) Multiome | 191 | |
| chr6:84,139,828–84,140,912 | 87.3 kb | Distal (>10kb) Multiome | 99 | |
| chr6:84,218,155–84,218,426 | 9.2 kb | Proximal (<10kb) | 57 | |
| chr6:84,227,112–84,228,449 | 76 bp | At TSS Multiome | 827 | |
| chr6:84,425,714–84,426,581 | 198.6 kb | Distal (>10kb) Multiome | 200 | |
| chr6:84,762,310–84,765,235 | 537.0 kb | Distal (>10kb) Multiome HiCAR | 714 | |
| chr6:84,772,862–84,775,261 | 547.3 kb | Distal (>10kb) Multiome HiCAR | 587 |
Genomic view of the CEP162 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.