Involved in cilium assembly. Located in centriolar satellite and ciliary basal body. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC113. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC113 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC113, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr16:57,984,418–57,986,121 | 264.9 kb | Distal (>10kb) Multiome | 447 | |
| chr16:57,999,954–58,001,881 | 248.7 kb | Distal (>10kb) Multiome | 920 | |
| chr16:58,024,574–58,028,306 | 224.4 kb | Distal (>10kb) Multiome | 1046 | |
| chr16:58,032,341–58,033,244 | 217.2 kb | Distal (>10kb) Multiome | 283 | |
| chr16:58,128,725–58,130,027 | 120.5 kb | Distal (>10kb) Multiome | 1095 | |
| chr16:58,197,509–58,198,705 | 51.8 kb | Distal (>10kb) Multiome | 490 | |
| chr16:58,236,247–58,236,852 | 13.4 kb | Distal (>10kb) Multiome | 355 | |
| chr16:58,243,466–58,244,046 | 5.9 kb | Proximal (<10kb) | 228 | |
| chr16:58,249,584–58,250,557 | 4 bp | At TSS Multiome | 641 | |
| chr16:58,392,269–58,393,124 | 142.6 kb | Distal (>10kb) Multiome | 993 | |
| chr16:58,463,143–58,465,363 | 213.7 kb | Distal (>10kb) Multiome | 307 | |
| chr16:58,487,547–58,488,283 | 237.9 kb | Distal (>10kb) Multiome | 523 | |
| chr16:58,499,699–58,500,457 | 250.0 kb | Distal (>10kb) Multiome | 283 | |
| chr16:58,500,548–58,502,121 | 251.5 kb | Distal (>10kb) Multiome | 481 | |
| chr16:58,511,772–58,512,394 | 262.1 kb | Distal (>10kb) Multiome | 355 | |
| chr16:58,515,027–58,516,681 | 265.6 kb | Distal (>10kb) Multiome | 1010 |
Genomic view of the CCDC113 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.