CAPN15
calpain 15 | SOLH

This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

Member of: DE-5 DE-5.24
Biological processes 9 terms
Expression (TPM)
CAPN15 — as a Regulated Gene

TFs regulating CAPN15 0 TFs

Transcription factors with Perturb-seq knockdown data for CAPN15. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CAPN15 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to CAPN15

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CAPN15, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr16:228,869–229,598 298.4 kb Distal (>10kb) Multiome 1035
chr16:234,152–235,669 292.9 kb Distal (>10kb) Multiome 908
chr16:351,804–354,436 174.8 kb Distal (>10kb) Multiome 654
chr16:378,999–379,813 148.3 kb Distal (>10kb) Multiome 225
chr16:380,836–382,614 145.7 kb Distal (>10kb) Multiome HiCAR 634
chr16:383,438–384,218 143.9 kb Distal (>10kb) Multiome HiCAR 342
chr16:396,893–397,640 130.2 kb Distal (>10kb) Multiome HiCAR 496
chr16:401,380–402,199 125.9 kb Distal (>10kb) Multiome HiCAR 818
chr16:424,888–426,136 102.1 kb Distal (>10kb) Multiome 752
chr16:483,333–484,000 44.0 kb Distal (>10kb) Multiome 143
chr16:526,749–528,601 120 bp At TSS Multiome 811
chr16:569,530–570,338 42.1 kb Distal (>10kb) Multiome 492
chr16:578,896–579,353 51.4 kb Distal (>10kb) Multiome 511
chr16:588,593–590,724 62.2 kb Distal (>10kb) Multiome 853
chr16:635,900–638,127 108.6 kb Distal (>10kb) Multiome 1021
chr16:641,491–643,007 114.2 kb Distal (>10kb) Multiome 856
chr16:648,795–649,829 121.6 kb Distal (>10kb) Multiome 862
chr16:660,457–661,656 133.2 kb Distal (>10kb) Multiome 456
chr16:667,633–668,442 140.3 kb Distal (>10kb) Multiome 838
chr16:678,847–681,585 152.3 kb Distal (>10kb) Multiome 803
chr16:683,618–684,859 156.7 kb Distal (>10kb) Multiome 701
chr16:694,897–695,485 167.7 kb Distal (>10kb) Multiome 390
chr16:705,242–706,468 178.3 kb Distal (>10kb) Multiome 248
chr16:714,577–716,048 187.4 kb Distal (>10kb) Multiome 555
chr16:720,434–721,963 193.6 kb Distal (>10kb) Multiome 966
chr16:726,310–729,144 199.3 kb Distal (>10kb) Multiome 736
chr16:740,359–741,596 213.4 kb Distal (>10kb) Multiome 897
chr16:787,564–789,160 260.8 kb Distal (>10kb) Multiome 635
chr16:807,352–808,044 280.1 kb Distal (>10kb) Multiome 600
chr16:813,330–813,960 286.1 kb Distal (>10kb) Multiome 325

Genome Browser

Genomic view of the CAPN15 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr16:218,869 – 823,960
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq