Predicted to be involved in spermatogenesis. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for C3orf62. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = C3orf62 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of C3orf62, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:48,989,537–48,991,069 | 286.8 kb | Distal (>10kb) Multiome | 552 | |
| chr3:49,006,738–49,008,496 | 269.0 kb | Distal (>10kb) Multiome | 955 | |
| chr3:49,017,789–49,018,870 | 258.4 kb | Distal (>10kb) Multiome | 780 | |
| chr3:49,020,066–49,022,597 | 255.0 kb | Distal (>10kb) Multiome | 1064 | |
| chr3:49,028,856–49,029,800 | 247.4 kb | Distal (>10kb) Multiome | 974 | |
| chr3:49,093,005–49,094,956 | 182.6 kb | Distal (>10kb) Multiome | 944 | |
| chr3:49,104,279–49,105,309 | 172.1 kb | Distal (>10kb) Multiome | 712 | |
| chr3:49,120,575–49,121,282 | 155.9 kb | Distal (>10kb) Multiome | 765 | |
| chr3:49,132,603–49,133,965 | 143.1 kb | Distal (>10kb) Multiome | 652 | |
| chr3:49,166,057–49,166,586 | 110.5 kb | Distal (>10kb) Multiome | 622 | |
| chr3:49,170,896–49,171,950 | 105.5 kb | Distal (>10kb) Multiome | 781 | |
| chr3:49,276,912–49,277,398 | 208 bp | At TSS Multiome | 291 | |
| chr3:49,339,607–49,340,853 | 63.4 kb | Distal (>10kb) Multiome | 1044 | |
| chr3:49,357,868–49,359,083 | 81.6 kb | Distal (>10kb) Multiome | 908 | |
| chr3:49,411,409–49,412,844 | 135.2 kb | Distal (>10kb) Multiome | 899 | |
| chr3:49,422,179–49,422,905 | 145.7 kb | Distal (>10kb) Multiome | 453 | |
| chr3:49,428,857–49,429,869 | 152.6 kb | Distal (>10kb) Multiome | 712 | |
| chr3:49,461,484–49,462,134 | 184.9 kb | Distal (>10kb) Multiome | 207 | |
| chr3:49,468,926–49,470,930 | 193.3 kb | Distal (>10kb) Multiome | 919 | |
| chr3:49,539,369–49,540,584 | 263.1 kb | Distal (>10kb) Multiome | 628 | |
| chr3:49,553,618–49,555,244 | 277.6 kb | Distal (>10kb) Multiome | 710 |
Genomic view of the C3orf62 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.