Enables RNA binding activity. Involved in ribosomal small subunit biogenesis. Located in chromosome. Part of small-subunit processome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for C1orf131. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = C1orf131 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of C1orf131, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:230,978,084–230,979,476 | 262.2 kb | Distal (>10kb) Multiome | 931 | |
| chr1:231,037,684–231,038,550 | 203.0 kb | Distal (>10kb) Multiome | 274 | |
| chr1:231,039,156–231,041,267 | 200.9 kb | Distal (>10kb) Multiome | 661 | |
| chr1:231,065,566–231,066,080 | 175.4 kb | Distal (>10kb) Multiome | 199 | |
| chr1:231,161,989–231,163,833 | 78.7 kb | Distal (>10kb) Multiome | 768 | |
| chr1:231,211,148–231,211,998 | 29.6 kb | Distal (>10kb) Multiome | 631 | |
| chr1:231,233,923–231,234,376 | 6.8 kb | Proximal (<10kb) | 288 | |
| chr1:231,240,746–231,241,633 | 88 bp | At TSS Multiome | 834 | |
| chr1:231,337,024–231,338,750 | 96.9 kb | Distal (>10kb) Multiome | 881 | |
| chr1:231,420,882–231,422,905 | 181.2 kb | Distal (>10kb) Multiome | 956 | |
| chr1:231,528,042–231,528,983 | 287.3 kb | Distal (>10kb) Multiome | 873 |
Genomic view of the C1orf131 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.