This transcribed locus is thought to be non-coding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Transcription factors with Perturb-seq knockdown data for ARRDC1-AS1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ARRDC1-AS1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ARRDC1-AS1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:137,406,843–137,407,556 | 211.7 kb | Distal (>10kb) Multiome | 427 | |
| chr9:137,422,664–137,424,024 | 195.5 kb | Distal (>10kb) Multiome | 896 | |
| chr9:137,441,270–137,441,970 | 177.2 kb | Distal (>10kb) Multiome | 568 | |
| chr9:137,453,153–137,455,543 | 164.8 kb | Distal (>10kb) Multiome | 727 | |
| chr9:137,458,468–137,459,887 | 159.5 kb | Distal (>10kb) Multiome | 613 | |
| chr9:137,461,555–137,462,160 | 156.9 kb | Distal (>10kb) Multiome | 284 | |
| chr9:137,551,136–137,552,512 | 67.1 kb | Distal (>10kb) Multiome | 756 | |
| chr9:137,578,523–137,579,553 | 39.9 kb | Distal (>10kb) Multiome | 910 | |
| chr9:137,589,526–137,591,323 | 28.2 kb | Distal (>10kb) Multiome | 623 | |
| chr9:137,604,440–137,607,003 | 13.4 kb | Distal (>10kb) Multiome | 675 | |
| chr9:137,618,064–137,619,880 | 113 bp | At TSS Multiome | 867 | |
| chr9:137,723,975–137,724,439 | 105.4 kb | Distal (>10kb) Multiome | 115 | |
| chr9:137,876,903–137,879,307 | 260.0 kb | Distal (>10kb) Multiome | 452 |
Genomic view of the ARRDC1-AS1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.