This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]

Biological processes 113 terms

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187)G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187)actin cytoskeleton organization (GO:0030036)actin filament (GO:0005884)adherens junction (GO:0005912)alpha-beta T cell differentiation (GO:0046632)alpha-beta T cell differentiation (GO:0046632)apical plasma membrane (GO:0016324)apical plasma membrane (GO:0016324)basolateral plasma membrane (GO:0016323)cadherin binding involved in cell-cell adhesion (GO:0098641)calcium ion binding (GO:0005509)calcium ion binding (GO:0005509)calcium ion binding (GO:0005509)calcium ion binding (GO:0005509)calcium-dependent phospholipid binding (GO:0005544)calcium-dependent phospholipid binding (GO:0005544)calcium-dependent phospholipid binding (GO:0005544)calcium-dependent protein binding (GO:0048306)calcium-dependent protein binding (GO:0048306)cell surface (GO:0009986)cell surface receptor signaling pathway (GO:0007166)cell-cell adhesion (GO:0098609)cellular response to glucocorticoid stimulus (GO:0071385)cellular response to glucocorticoid stimulus (GO:0071385)cellular response to glucocorticoid stimulus (GO:0071385)cellular response to vascular endothelial growth factor stimulus (GO:0035924)cilium (GO:0005929)cornified envelope (GO:0001533)cornified envelope (GO:0001533)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasmic vesicle (GO:0031410)cytoplasmic vesicle membrane (GO:0030659)cytosol (GO:0005829)early endosome (GO:0005769)early endosome membrane (GO:0031901)endosome (GO:0005768)endosome membrane (GO:0010008)extracellular exosome (GO:0070062)extracellular exosome (GO:0070062)extracellular exosome (GO:0070062)extracellular matrix (GO:0031012)extracellular region (GO:0005576)extracellular region (GO:0005576)extracellular region (GO:0005576)extracellular region (GO:0005576)focal adhesion (GO:0005925)granulocyte chemotaxis (GO:0071621)inflammatory response (GO:0006954)inflammatory response (GO:0006954)inflammatory response (GO:0006954)keratinocyte differentiation (GO:0030216)lateral plasma membrane (GO:0016328)lateral plasma membrane (GO:0016328)lipid binding (GO:0008289)membrane (GO:0016020)monocyte chemotaxis (GO:0002548)motile cilium (GO:0031514)motile cilium (GO:0031514)myoblast migration involved in skeletal muscle regeneration (GO:0014839)negative regulation of T-helper 2 cell differentiation (GO:0045629)negative regulation of apoptotic process (GO:0043066)negative regulation of exocytosis (GO:0045920)negative regulation of interleukin-8 production (GO:0032717)negative regulation of transport (GO:0051051)neutrophil activation (GO:0042119)neutrophil clearance (GO:0097350)neutrophil homeostasis (GO:0001780)neutrophil homeostasis (GO:0001780)nucleoplasm (GO:0005654)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)peptide cross-linking (GO:0018149)phagocytic cup (GO:0001891)phagocytosis (GO:0006909)phagocytosis (GO:0006909)phagocytosis (GO:0006909)phosphatidylserine binding (GO:0001786)phospholipase A2 inhibitor activity (GO:0019834)phospholipase A2 inhibitor activity (GO:0019834)phospholipase inhibitor activity (GO:0004859)phospholipid binding (GO:0005543)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)positive regulation of T cell proliferation (GO:0042102)positive regulation of T-helper 1 cell differentiation (GO:0045627)positive regulation of cell migration involved in sprouting angiogenesis (GO:0090050)positive regulation of interleukin-2 production (GO:0032743)positive regulation of multicellular organismal process (GO:0051240)positive regulation of neutrophil apoptotic process (GO:0033031)positive regulation of vesicle fusion (GO:0031340)positive regulation of vesicle fusion (GO:0031340)positive regulation of wound healing (GO:0090303)protein binding (GO:0005515)regulation of cell shape (GO:0008360)regulation of hormone secretion (GO:0046883)regulation of inflammatory response (GO:0050727)regulation of inflammatory response (GO:0050727)regulation of interleukin-1 production (GO:0032652)regulation of interleukin-1 production (GO:0032652)regulation of leukocyte migration (GO:0002685)regulation of leukocyte migration (GO:0002685)sarcolemma (GO:0042383)signal transduction (GO:0007165)signal transduction (GO:0007165)signaling receptor binding (GO:0005102)vesicle (GO:0031982)vesicle membrane (GO:0012506)