Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ANKRD37. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ANKRD37 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ANKRD37, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr4:185,115,806–185,116,379 | 280.7 kb | Distal (>10kb) Multiome | 365 | |
| chr4:185,127,221–185,129,177 | 269.2 kb | Distal (>10kb) Multiome | 406 | |
| chr4:185,142,664–185,143,838 | 253.6 kb | Distal (>10kb) Multiome | 886 | |
| chr4:185,203,468–185,204,322 | 192.8 kb | Distal (>10kb) Multiome | 710 | |
| chr4:185,209,029–185,211,342 | 187.3 kb | Distal (>10kb) Multiome | 699 | |
| chr4:185,235,783–185,236,350 | 160.8 kb | Distal (>10kb) Multiome | 289 | |
| chr4:185,318,614–185,319,089 | 77.9 kb | Distal (>10kb) Multiome | 382 | |
| chr4:185,395,863–185,397,395 | 176 bp | At TSS Multiome | 1140 | |
| chr4:185,425,371–185,426,547 | 29.3 kb | Distal (>10kb) Multiome | 873 | |
| chr4:185,470,476–185,472,157 | 74.6 kb | Distal (>10kb) Multiome | 628 | |
| chr4:185,534,729–185,535,832 | 138.6 kb | Distal (>10kb) Multiome | 535 | |
| chr4:185,559,542–185,560,280 | 163.1 kb | Distal (>10kb) Multiome | 164 | |
| chr4:185,650,774–185,651,628 | 254.4 kb | Distal (>10kb) Multiome | 184 |
Genomic view of the ANKRD37 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.